At H4Y, our team, advisors, investors, clients and partners are all united in one purpose - to accelerate medical research. To accomplish this purpose, our team is creating a suite of services to meet the needs of researchers, innovative companies, patients, healthy consumers, and healthcare providers as they pertain to medical research.
The software tools our company is building, and partnerships we are making, are efforts to increase the national average of participation in research from 2% annually to 29%, thereby decreasing delays in research by an average of 4.6 months, and costs by as much as 46%.
Our Advisory Board consists of operational and industry experts in their fields who believe in the value we are adding to the world, have experience delivering value in their own capacities, and dedicate their time and resources to help our company in making a positive impact on our customers' lives.
Ryan Bethencourt has nearly a decade of experience at three of the Big Seven CROs in the world. Most recently, he joined ICON Clinical Research (PhIb-IV) in 2012 as Director of Business Development with responsibilities for managing business and corporate development and establishing strategic clinical collaborations in the San Francisco / Bay Area and Pacific Northwest.
Prior to joining ICON, Ryan has had a decade of biopharma experience -- which has included seven years of Clinical Development experience working with PAREXEL as Director of Business Development for the West coast focusing on Phase I/II Clinical Development Programs and at Quintiles as the European Business Development Manager, having worked in partnership with most major Pharmaceutical and emerging Biotech companies in the US/EU to successfully conduct a broad range of translational clinical development studies.
Earlier in his career, Ryan worked in a variety of sales and business development roles within Pfizer, Merck and Cephalon (during which he identified and recommend the acquisition of CIMA labs, which was acquired for $482.5M USD).
Ryan received a Master’s in Bioscience Enterprise (an MBA/Biotech fusion course) from the University of Cambridge and a BSc degree in Biology and Genetics from the University of Warwick. Ryan is also a published author in the field of Biotechnology Business Development and is involved with start-up Biotech ventures.
Ryan also is involved with Halpin Neurosciences - a seed funded venture to find a therapy for ALS; Rawflow.com - VC funded by Benchmark Capital with £2M; Genescient Pharma division - Adviser and former P/T COO (helped close first external angel round)
Ricky Yean is Co-Founder and CEO of Crowdbooster.com. Crowdbooster is an angel-backed startup from the Y Combinator Summer 2010 batch, developing social media optimization software based on artificial intelligence and machine learning to help marketers get the most out of social media.
Ricky graduated from Stanford University with a degree in Science, Technology and Society in 2010. He now serves on the Board of Advisors of BASES, one of the largest student entrepreneurship organizations in the nation.
Kevin has spent most of the past 28 years either managing research groups or running his own experiments at the bench. He is co-founder and CEO of Assay Depot, which owns and operates a network of online research exchanges that have the potential to dramatically improve how research outsourcing is done. In 2001, Kevin co-founded Kalypsys, a fully integrated drug discovery company that raised over $170 million in venture funding and put five drug candidates into human clinical trials.
Prior to Kalypsys, he directed lead discovery at Tularik, a highly successful biopharmaceutical company purchased by Amgen for more than $2 billion. He carried out postdoctoral work in Cell Biology at Harvard Medical School after receiving a PhD degree from Marc Kirschner's laboratory in the Department of Biochemistry & Biophysics at the University of California, San Francisco (UCSF). Kevin has a M.S. degree in Biochemistry from the University of Missouri, Columbia and an A.B. degree, magna cum laude, in Molecular and Cell Biology from Cornell University's College of Arts and Sciences. His research discoveries have been published in Science magazine and other leading scientific journals and he has been awarded eight technology patents.
Caleb is finishing his research in Biomedical Informatics. At the University of Texas, Houson, Caleb is applying models of human cognition to information retrieval.
Currently, he is leveraging ACT-R and the rational analysis of human memory to create a theoretically driven retrieval model and document ranking method for retrieving information using existing biomedical knowledge sources. His previous and primary research as a graduate student at the University of Memphis was developing computational knowledge models for sensors and developing a framework leveraging the computational knowledge model to support dynamic discovery and synchronization of senor services to support high-level user constraints. The research at The University of Memphis was conducted under Dr. David J. Russomanno in the Department of Electrical and Computer Engineering.
Caleb Describes is skilled in information retrieval (query log mining, information foraging theory, and Bayesian models), artificial intelligence, computational cognitive architectures, text mining (distributional semantics) Academic History PhD in Biomedical Informatics | 2008-Present The University of Texas Health Science Center, School of Biomedical Informatics MS in Biomedical Informatics, The University of Texas Health Science Center 2011 MS in Electrical Engineering , The University of Memphis 2007 BS in Computer Engineering , The University of Memphis 2005
Eskander Matta is vice president of eBusiness at Blue Shield of California, a 3.4 million member, $9 billion not-for-profit California health plan that provides health and life insurance products for the commercial, individual and government markets. Matta leads the product management, strategy, customer experience, product development and operations of Blue Shield’s eBusiness portals.
Matta comes to Blue Shield with more than 17 years of experience in strategic management consulting, systems integration, investment banking, and global advertising. Most recently, he led various internet/eCommerce functions at Wells Fargo as Senior Vice President of the Internet Services Group, managing wellsfargo.com and online sales and the online payments, the small business customer segment, and mobile banking businesses. Matta has also held positions at Mercer Management Consulting, CSC Index, Credit Suisse First Boston, Organic Online, and Bates Advertising.
Matta graduated magna cum laude from the University of California, Berkeley with a dual degree in Economics and History and subsequently earned an MBA from Harvard Business School.
Matta resides in Silicon Valley with his wife and two young daughters. He enjoys travelling, having visited over 100 countries, reading, and yoga.
Ryan currently advises the national government on health policy, serving on the Consumer Empowerment Workgroup of the Health IT Policy Committee (HITPC) for the Office of the National Coordinator at the Department of Health and Human Services. Ryan is also on the Communications team at the Society for Participatory Medicine. Previously, Ryan served in multiple capacities leading Meaningful Use, account management, customer/product development, business development, and hiring at the leading iPad Electronic Health Record company (drchrono.com). Prior, Ryan founded a nonprofit to educate and empower consumers to make a difference in healthcare. Ryan began his career in healthcare to help his grandfather battle nonsmall cell lung cancer, and continues pursuing all ventures with that same personal fervor he had with his grandfather.
Ryan enjoys basketball, dancing, watching comedy and movies, and catching up with friends during spare time.
Mr. Tsai serves as H4Y’s Chief Executive Officer. Previously, Mr. Tsai was responsible for engaging with existing and prospective partners interested in taking advantage of H4Y's technology to accelerate their clinical research. As an experienced scientist, Mr. Tsai has a penchant for new technology - he previously managed a research group at UC Irvine, spearheading the creation of a novel brain-damage-analysis protocol, and conducted research and development in endocrinology for Quest Diagnostics. He also cofounded an education company focused on leveling the academic playing field for health-impacted students. When off duty, Mr. Tsai is an avid snowboarder, cyclist, and all-around adventurer with a fancy camera.
Dr. Saeed Sadeghi is a full-time staff physician and assistant clinical professor of medicine in the Division of Hematology/Oncology at the David Geffen School of Medicine at UCLA. He serves as the medical director of the UCLA hematology/oncology outpatient clinic in Santa Monica.
After earning his medical degree from St. Louis University School of Medicine, he completed an internal medicine residency at the Keck School of Medicine at the University of Southern California and subsequently, a fellowship in hematology/oncology at UCLA. While keeping a busy practice, he is an active member of the clinical research program at UCLA in gastrointestinal and breast malignancies.
Cooley has more than 700 lawyers across eleven offices in the United States and China. Cooley’s attorneys solve legal issues for entrepreneurs, investors and established companies. Clients partner with Cooley on transformative deals, complex IP matters and bet-the-company litigation, often where innovation meets the law.
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